Bahrain will suspend dine-in services at restaurants and cafes and move public and private schools to remote learning for three weeks to contain the spread of the coronavirus, the health ministry said.
It said it had detected a new variant of coronavirus in a number of cases, without specifying which kind.
The new lockdown measures will come into effect on Sunday.
There has been an uptick in coronavirus cases in the Gulf kingdom since December. The country registered 459 new cases on Wednesday, adding to a total of nearly 100,000 since the start of the pandemic, with 370 deaths.
The small island state has the third highest rate of vaccinations per capita in the world so far, according to the Our World in Data website, which is run by an Oxford University research programme.
Bahrain offers its citizens either the Pfizer/BioNTech vaccine or one manufactured by Chinese state-backed pharmaceutical giant Sinopharm free of charge.
The kingdom also approved the AstraZeneca COVID-19 vaccine on Monday for emergency use.
At least 5 were killed and 35 others injured when a bomber detonated an explosive inside a mosque in Maiduguri, the capital of Nigeria's Borno state, during evening prayers, police said.
A helicopter has crashed on Tanzania's Mount Kilimanjaro, killing five people, the civil aviation authority said on Thursday, while local media reported that the aircraft was on a medical rescue mission.
Fourteen countries including Britain, Canada, and Germany have condemned the Israeli security cabinet's approval of 19 new settlements in the occupied West Bank on Wednesday, saying they violated international law and risked fuelling instability.
The US Justice Department has found more than a million more documents potentially tied to convicted American financier Jeffrey Epstein, delaying a full release for weeks while officials redact details to protect victims, the Department of Justice said on Wednesday.