Chile has pulled out of hosting two major international summits, including a UN climate change conference.
President Sebastian Pinera made the announcement as anti-government protests continue in the country.
He said his government needs "to prioritise re-establishing public order".
The UN is looking into alternative venues for the December's COP25 climate summit and next month's Apec trade forum.
Iran, Israel launch new attacks as Tehran rules out nuclear talks
Iran and Israel exchanged fresh attacks early on Saturday, a day after Tehran said it would not negotiate over its nuclear programme while under threat and Europe tried to keep peace talks alive.
UN's Guterres urges 'give peace a chance' in Israel-Iran conflict
UN Secretary-General Antonio Guterres warned on Friday that expansion of the Israel-Iran conflict could "ignite a fire no one can control" and called on both sides and potential parties to the conflict to give peace a chance.
Israel-Iran conflict deepens, European diplomacy steps in
As the air war between Israel and Iran enters its second week, the foreign ministers of Britain, France and Germany are making renewed efforts to draw Iran back to negotiations, while US involvement remains undecided.
Death toll rises in Gaza as aid-seeking crowds come under fire
Dozens of Palestinians have been killed by Israeli fire in the past two days while trying to access food aid in Gaza, amid a worsening hunger crisis, according to local medics.
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