American teenager Coco Gauff comes up against Venus Williams in the first round, while top seed Ashleigh Barty kicks off her campaign against Lesia Tsurenko of Ukraine.
Defending champion Naomi Osaka will face Marie Bouzkova of the Czech Republic, while Serena Williams faces Anastasia Potapova in her quest for a 24th Grand Slam title.
In the men's round, Roger Federer has been drawn in the same half as Novak Djokovic, meaning they could meet in the semi-finals.
The Swiss star starts against American Steve Johnson, while Djokovic opens his campaign against Germany's Jan-Lennard Struff.
Spanish top seed Rafael Nadal plays against Bolivia's Hugo Dellien in the first round.
The first Grand Slam of the year kicks off on January 20.
Atalanta progressed to the Europa League semi-finals despite losing 1-0 to Liverpool on Thursday as they triumphed 3-1 on aggregate to move one step closer to a first ever European final for the Serie A side.
Antonio Ruediger scored the decisive penalty as Real Madrid beat holders Manchester City in an edge-of-your-seat 4-3 shootout victory to reach the semi-finals of the Champions League after the teams were locked at 4-4 on aggregate following extra time on Wednesday.
Bayern Munich's Joshua Kimmich powered in a 63rd-minute header to give them a 1-0 victory over a toothless Arsenal on Wednesday and send them through to the Champions League semi-finals for the first time in four years with a 3-2 aggregate win.
Rafael Nadal said it was a challenge to hold himself back on his return to the ATP Tour after three months on the sidelines but the fiercely-competitive Spaniard expects to continue with the controlled approach in Barcelona.