According to manager Ole Gunnar Solskjaer, the France midfielder needs an operation on his ankle.
The 26-year-old only made his comeback last month, as his ankle problem kept him out since late September last year.
Scott McTominay is currently also out injured.
Pogba has played only eight times this season after having surgery to correct another ankle injury.
F1 commission agrees to shorter races from 2027
The governing FIA's Formula One commission has agreed on Monday to reduce the standard Grand Prix distance from 305km to 290km from 2027, cutting races by two or three laps.
Spain extend coach Luis de la Fuente to 2032
The Royal Spanish Football Federation (RFEF) has announced Monday that its board of directors has unanimously approved an extension of coach Luis de la Fuente's contract until 2032.
Infantino says he is open to talks over FIFA reform
FIFA President Gianni Infantino proposed an outside review of how the governing body makes major decisions on Monday, acknowledging in a letter to members that its handling of a now-abandoned investment plan had caused concern.
Troubled Marseille lose fifth straight as PSG win
Captain Marquinhos has snatched the winner as champions Paris St Germain won 2-1 at troubled Olympique de Marseille in Ligue 1 on Sunday, condemning the hosts to a fifth successive loss and a spot in the relegation zone.
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