After bowling out their hosts for 222, Sri Lanka ended the opening day on 60 for 3.
The tourists, who are fresh off their miracle one wicket win in the opening Test last week, need a win or a draw to secure a historic series result.
Day two gets underway at 12 PM UAE time.
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Kazuki Yabuta struck out eight and allowed only four hits and one run in 6.1 innings, and Haru Yoshioka had a perfect 2.2 relief with seven strikeouts, including a Fire Ball strikeout to end the game, to give Mid East Falcons the win 5-1 over Mumbai Cobras and tie the United Series (1-1).
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