The Shanghai Marathon has been postponed indefinitely, said the organisers of the run in a post on their website, amid rising COVID-19 cases in China.
"Today, we've chosen to be cautious, chosen to put the health of runners and city's citizens first," said the notice.
Runners entered in the November 28 race were given the opportunity either to give up their place or hold it until 2022.
Both the Beijing and Wuhan marathons have been called off with new dates yet to be determined.
China reported 62 new coronavirus cases for November 8.
Sabalenka, Djokovic headline US Open mixed doubles field
Infantino accuses World Cup critics of spreading hate in open letter
All-rounder Greaves sets test record with five wicket maidens in a row
Pogacar wins record-equalling fifth Tour de France title
