Top seed Karolina Pliskova has crashed out of the US Open following a straight-sets defeat in the second round.
The world no.3 lost 6-1, 7-6 (2) to France’s Caroline Garcia, who will now face 28th seed, American Jennifer Brady.
Elsewhere, sixth seed Petra Kvitova overcame a shaky start to defeat Kateryna Kozlova 7-6 (3), 6-2 in her second-round match, while the 2018 champion, Naomi Osaka, cruised past Camila Giorgi 6-1, 6-2.
In the men’s draw, top seed Novak Djokovic overcame Kyle Edmund 6-7 (7-5), 6-3, 6-4, 6-2 to set up a third-round matchup against No. 28 Jan-Lennard Struff.
Fourth seed Stefanos Tsitsipas also advanced to the third round following a 7-6 (2), 6-3, 6-4 win over wild card Maxime Cressy.
We need to find answers to stop Liverpool slide, says Slot
Rohit and Kohli bid likely farewell to Australia as winners
Al Wahda defeats Al Dhafra, heads to quarter-finals of UAE President's Cup
Bencic battles past Kenin to set up Noskova final in Tokyo
